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红芪多糖抗衰老作用的实验研究
On the Anti-aging Effect of Hedysarum Polysaccharide
【摘要】 红芪多糖(HPS)能明显延长果蝇的寿命,提高老年小鼠对有害刺激的非特异性抵抗力,降低动物血浆中过氧化脂质含量,减少脂褐素形成,并可清除细胞中已形成的脂褐素。大小剂量组对老年大鼠红细胞SOD含量均有明显地提高,可明显升高老年大鼠血清皮质醇及睾酮。HPS150mg/kg对各脏器RNA含量均见明显增加,可显著提高中性粒细胞活性,改善老年鼠T细胞对抗原刺激的应激性,与环磷酰胺组动物有明显差异。
【Abstract】 Hedysarum polysaccharide (HPS) can prolong the life-span of drosophlia; enhances nonspecific resistance of aged mice against noxious stimuli; loowers plasma LPO; decreases the formation of lipofusin with eventual elimination; increases erythyrocyte SOD; elevates serum cortisol and androsterone level in aging rats at various doses. Markedly increases RNA content of viscera; enhances the activity of neutrophilic granulocyte and improves the irritability of T cells in againg mice toward antigenic stimuli in contrast to those treated with cyclophosphamide.
- 【文献出处】 中草药 ,Chinese Traditional and Herbal Drugs , 编辑部邮箱 ,1992年09期
- 【分类号】R285.5
- 【被引频次】57
- 【下载频次】72