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石菖蒲对小鼠学习记忆的促进作用

Facilitatory Effects of Grassleaf Sweetflag (Acorus gramineus) on learning and memory in mice

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【作者】 周大兴李昌煜林乾良

【Author】 Zhou Da-xing, Z(?)ng College of Traditional Chinese Medicine, Hangzhou Li Chang-yu and Lin Qian-liang

【机构】 浙江中医学院

【摘要】 采用复杂食饵性迷宫法和一次性训练被动回避条件反应一跳台法,观察石菖蒲水提醇沉液对学习记忆的促进作用和改善记忆障碍作用。结果表明:石菖蒲(0.1g/10g,0.2g/10g相当于LD50的1/54,1/27)灌服能明显促进正常小鼠的记忆获得和改善东莨菪碱、亚硝酸钠、乙醇造成的记忆获得,巩固和再现障碍,并与脑复康作了比较。

【Abstract】 Rhizoma of Acorus gramimineus on memory in mice was studied using one trial passive avoidance respones-step-down test and complicated grub maze. Results indicated that rhizoma of A. gramineus (0.1g/10g, 0.2g/10g) facilitated consolidation of memory, and improved impairment of acquisition, consolidation, retrieval of memory produced by scopolamine, sodium nitrite and alcohol. Piracetam was used for comparison.

  • 【文献出处】 中草药 ,Chinese Traditional and Herbal Drugs , 编辑部邮箱 ,1992年08期
  • 【分类号】R285.5
  • 【被引频次】57
  • 【下载频次】63
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