【摘要】 由安徽屯溪绿茶分离得到的茶叶多糖有:①抗凝作用。体外可显著延长混合人血浆的凝血时间和凝血酶元时间;灌胃给药:50mg/kg,小鼠凝血时间延长319%;37mg/kg,家兔凝血酶元时间延长40%。②抗血栓作用。灌胃给药37mg/kg,可抑制家兔实验性血栓形成,血栓形成时间明显延长,血栓长度缩短;血小板数减少20%,血小板粘附率降低43%,全血粘度及血浆粘度分别降低16%和11%,红细胞压积降低20%,血沉增加75%。灌胃给药40mg/kg,豚鼠纤维蛋白溶解酶活力增加77%。更多还原

【Abstract】 Polysaccharides isolated from green tea leaves (TLP) presented the following pharmacological activities:(1) Anticoaguation and promotes fibrinolysis:TLP prolonged coagulation time and prothrombin time of mixed human plasma in vitro; lengthened coagulation time by 319% at 50mg/kg (po); Prolonged prothrombin time in rabbity by 40% at 37mg/kg (po) and speeded up fibrinolysin vigor in guinea pigs by 77% at a dose of 40mg/kg (po).(2) Antithrombosis:TLP 37mg/kg (po) abviously inhibited experimental thrombus formation. Blood platelet count, platelet adherence rate, whole blood viscosity, plasma viscosity and hematocrit in rabbits decreased by 20%, 43%, 16%, 11% and 20% respectively while erythrocyte sedimentation rate increased by 75%.更多还原