【摘要】 本实验研究是以脾淋巴细胞电泳率(SL-EPM)为指标,探讨维生素E(VE)对脾淋巴细胞膜辐射损伤的防护作用。结果表明:小鼠经过含100ppm VE的饲料饲喂6周,VE对4.8Gy X-射线照射所引起的SL-EPM修饰产生明显的辐射防护效应;全身照射实验与体外照射实验的结果是一致的。据此可认为,VE对辐射所致SL-EPM修饰的抑制作用,是VE维持细胞膜稳定性的一种生理功能。更多还原

【Abstract】 The spleen lymphocyte electrophoretic mobility was used as an indicator for determining the effect of vitamin E (VE) oa protecting the spleen lymphocyte membrane from irradiation injury. The result demonstrated that after whole body irradiation of mice with 4.8 Gy X-ray, the spleen lymphocyte electrophoretic mobility (SL-EPM) of the animals administered 100ppm VE for six weeks was significantly higher than that of the control (p<0.05), which accorded with the results obtained in vitro. It is suggested that the protective effect of VE on modification of SL-EPM induced by irradiation may be due to keeping the stability of cell membrane.更多还原