【摘要】 我们观察了23例急性胰腺炎病人的血浆TXB₂和6—Koto-PGF_1α的水平,并应用复方丹参对患者进行治疗。结果表明:急性胰腺炎中血浆TXA₂和PGI₂的水平出现明显的不平衡;复方丹参能明显降低血浆TXA₂水平,相对增加PGI₂的生成,有改善胰腺的微循环,促使胰腺炎康复的作用与激素和优布芬比较,具有更好的治疗价值。更多还原

【Abstract】 In order to study the changes of prostagladin in acute pancreatitis, the plasmas level of TXA₂ and 6—Keto—PGF_1α, the stable metabolites of TXA₂ and PGI₂, have been measured by ELISA techniques in 23 patients with acute pancreatitis. A marked increases in TXB₂ levels and a slight inereas in 6—Ke-to—PGF_1α levels were found in plasma of early acute pancreatitis. The TXB₂ to 6—Keto—1GF_1α ratio was not changed. The plasma levels of 6—Keto—PGF_1α continued to inerease but the plasma levels of TXB₂ fell singnificantly in later time of pancreatitis. The TXB₂ to 6—Keto—PGF_1α ratio was markly reduced. Salviae miltiorrhiza can improve the microcirculatory blood flow in pancreas. After the treatment of acute panereatitis with salviae miltrorrhiza, the diminished plasma levels of TXB₂ and the increased plasma levels of 6—Keto—PGF_1α were observed. Salviae miltiorrhiza may provide some help in the treatment of acute pancreatitis.更多还原