【摘要】 急性心肌梗死患者62例,其中31例(男18例,女13例;年龄60±4a)给常规疗法加美西律口服,150mg,tid,4wk为一个疗程。另31例(男20例,女11例;年龄60±5a)为常规组(静脉输极化液及对症处理),2组常规治疗相同。4wk后比较:室性及危重警告性心律失常美西律组明显低于对照组(32％对68％,6％对26％)P<0.01.更多还原

【Abstract】 Among 62 acute myocardial infarction (AMI) patiemts, 31. patients (M 18. F 13; age 60+4 a) received routine therapy (polarizatipn and symptomatic treatment) and mexiletine 150 mg po, tid for 4 wk. Meanwhile, 31 AMI patients (M 20,F11 age 60+5a) received routine therapy only for comparison. The results revealed that ventricular arrhythmia and risking ventricular arrhythmia (paroxysmal ventricular tachycardia, R on T, ventricular fibrillation) in the mexiletine group were 32% and 6%, respectively; but in the routine therapy group, 68% and 26%, respsctively (P<0.01). To conclude, it is advised to supplement mexiletine on top of the routine therapy.更多还原