【摘要】 分别用自体骨骼肌和坐骨神经修复34只Wistar大鼠的68根坐骨神经缺损。术后15、30、60天检测腓肠肌、比目鱼肌收缩力、再生轴索通过率及直径,并应用电子显微镜观察神经再生。术后60天,自体神经移植组有良好的功能恢复,自体骨骼肌移植虽有部分功能恢复,但与自体神经移植组的差异有显著的统计学意义。作者等认为,自体骨骼肌作为移植体桥接大鼠坐骨神经缺损虽可获得一定的神经再生,但能否用于修复周围神经缺损尚需进一步研究。更多还原

【Abstract】 Autogenous skeletal muscles or sciatic nerves were used as grafts to bridge the gaps between severed ends of 68 sciatic nerves in 34 Wistar rats, Nerve axons regeneration in these grafts was assessed individually 15, 30 and 60 days after operation respectively with the following criteria,i.e. contractility of Musculi gastrocnemius and Musculi soleus, diameters, rates of crossing-over and ultrastructures of the regenerated axons. Two months after operation the group with sciatic nerve as graft gained satisfactory functional recovery. The group with skeletal muscle as graft gained some functional recovery partially with their data significantly different from those of the nerve tissue group statistically. In the authors’ opinion, although some nerve regenerative functions have been found with skeletal myscle grafts, utilization of the latter for reliable repairing needs to be studied further.更多还原