【摘要】 本研究采用血管墨汁灌注方法、血管塑料铸型方法,结合扫描电镜和透射电镜。观察了血吸虫病鼠(n=10)和兔(n=10)肝内微血管的变化。发现血吸虫病动物肝内门脉分支中断,肝窦数目减少,肝静脉分支扭曲、变形,肝窦毛细血管化,肝窦内皮细胞损伤,肝窦内有白细胞嵌塞。表明血吸虫病肝不仅有窦前梗阻,肝窦内及窦后亦有梗阻因素存在。更多还原

【Abstract】 At present experiment, we studied the microvaseulature changes of mice(n=10) and rabbits(n=10) with chronic schistosomiasis, using ink perfusion example, resin vascular casts and eletron microscope. The results show the decrease of liver sinusoid number, tortuosity of terminal hranehes of the portal vein, formation of a basement membrane in the space of Disse, capillarization of the sinusoid. The results suggest that the sinusoidal and postsinusoidal blockage can contribute to schistosomiasis portal hypertension.更多还原