【摘要】 报道了合成铜（Ⅱ）、金（Ⅲ）的 N—5—硝基-2-呋喃甲醛缩氨基硫脲（N-FDTSCH）和2-乙酰吡啶缩氨基硫脲（2-APTH）的四种新配合物:Cu（N-FDTSC）Cl（Ⅱ）、Au（N-FDTSCH）₂Cl₃（Ⅲ）、Cu（2-APTH）Cl₂·H₂O（V）和 Au（2-APTH）₂Cl₃（Ⅵ）。基于元素分析、摩尔电导、紫外和红外谱及热谱等对它们的组成和成键情况进行了讨论。体内和体外抗炎活性实验表明配合物 V具有较高的抗炎活性,且毒性较小。更多还原

【Abstract】 Four new complexes’of Cu（N-FDTSCH）Cl,Au（N-FDTSCH）₂Cl₃,Cu（2-APTH）Cl₂· H₂O and Au（2-APTH）₂Cl₃,where N-FDTSCH stands for 5-nitro-furaldehyde thiosemicarbazone and 2-APTH for 2-acctylpyridinc thiosemicarbazone have been isolated directly by rcaction of CuCl₂ and AuCl₃ to N-FDTSCH and 2-APTH, respectively.These complexes have been characterized by the elemental analysis,molar condutance,UV and IR spectroscopy,TG and DTG techniques.Over and above this,the inhibition effects on the heat denaturation of human aerum gamma globulin in vitro and the antiinflammatory activities in vivo of the synthesized compounds have been investi- gated.更多还原