【摘要】 本实验用免疫细胞化学技术观察了不同年龄金黄地鼠视皮层和上丘中P物质(SP)阳性神经元数量和分布的变化,同时观察了不同年龄金黄地鼠视皮层SP阳性神经元的形态和类型。结果表明,出生后10天小鼠视皮层SP阳性神经元为36％,Ⅱ—Ⅳ层密度最大,约占40％。上丘中SP阳性神经元约为37％。出生后20天,视皮层及上丘中SP阳性神经元分别减少到23％和16％。视皮层Ⅱ—Ⅳ层减少最明显,Ⅴ层和Ⅵ层变化不大。成年鼠视皮层及上丘中偶见SP神经元,但出现一些SP阳性纤维。出生10天及20天鼠视皮层中SP阳性神经元的形态及类型没有差别。更多还原

【Abstract】 The number, distribution and type of substance P-containing neurons of the visual centres at the different postnatal stages of the hamster have been studied with the aid of immunocytochemical technique. The percentage of substance P-immunoreactive neurons of the visual cortex of the hamster on the 10th day postnatal is 36%.There is a highter percentage of substance P neurons in layers II"IV; it is about 40% .In the colliculus superior , the SP-immunopositive neurons occupy 37%. On the 20th day (postnatal) the SP neurons in the visual cortex and colliculus superior are decreased to 23% and 16% respectively. In the visual cortex and colliculus superior of adult hamster, only a few substance P-containing neurons can be seen, but some SP-containing fibers appeared. The results show that the number of SP neurons in visual centre is decreasing with the growth of the ages and the SP-immunoreaction can take place in neurons of different types.更多还原