【摘要】 研究了47名铅中毒工人某些内分泌腺功能.发现血中T₃、T₄、皮质醇、TSH水平明显低于配对对照组,差别有高度显著性（P<0.001）,除TSH外均与工龄呈负相关,提示铅可能损伤甲状腺、肾上腺皮质、垂体前叶致使铅中毒工人产生甲状腺和肾上腺皮质功能低下的症状,说叨铅损伤某些内分泌腺功能可能是铅中毒的重要机制之一。更多还原

【Abstract】 In this paper, we studied the functionof some endocrine glands in 47 workers ofead poisoning. The results showed that thelevels of T₃. T₄, TSH and Cortisol in theserum are markedly lower in the group oflead poisoning than those of the control gr-oup and the difference is quite significant（P<O. O01）. All the levels except TSH sho-wed negative correlation with duration ofexposure. The results suggested that leadmay impair the function thyroid gland, adr-enal cortex and anterior lobe of hypophys-is, and then lead to a series of clinical sy-mptoms of hypofunction of those glands. Inconclusion, the impairement of some endo-crine glands by lead may be also one of theimportant mechanisms of lead poisoning.更多还原