【摘要】 作者对经临床和组织学确诊的235例口腔粘膜白斑患者进行l～16年追踪随访,有32例白斑恶变,癌变率为13.6％。其中男性18例,占男性白斑数的11.8％;女性14例,占女性白斑数的16.9％。癌变组平均年龄为53.4岁。白斑类型以颗粒型和疣状型恶变率较高。癌变损害部位以舌部白斑恶变率最高占75％,尤以舌缘、舌腹损害为多。白斑出现疼痛,局部充血红斑,损害迅速扩大、糜烂、增殖质硬等,都可能为恶变的征兆。本组32例,术后随访到20例,有2例复发,术后中位生存期为8.5年。预后较好。更多还原

【Abstract】 235 cases of Oral Leukoplakia, which was confirmed histologically, had been observed and followed-up for 1-16 years. 32 cases of them were malignancy changed, The incidence was 13. 6%. The ratio in 18 male cases was 11. 8% and 14. 9% in female ones. The mean age of malignancy changing group was 53. 4 years. The higher malignancy changing rate was shown in the granulation type and verrucous form type. The more often involved site was the tongue and the incidence was 75%, especially in the border and dorsal of the tongue. This study suggested that the pain display, local congestion, macule, the enlargement of the lesion proliferation, ulceration and firm of the mass were all the bodements of malignancy change. In this paper total 32 cases were followed-up 2 cases got recovery, the prognosis was good.更多还原