【摘要】 用放射免疫分析法检测100例正常健康人在4℃和-30℃贮存的4种尿标本,即晨尿、饮水后1h尿、随意尿及24h全尿的β₂-微球蛋白（β₂-MG）、白蛋白（ALb）、IgG和糖蛋白（THP）,并进行了相关测定和t检验。表明2种温度贮存的尿标本,4种蛋白检测结果无显著差异。ALb、IgG和THP的测定值在随意尿和24h尿最有相关性,γ分别为0.7565,0.7845及0.7837。β₂-MG则在饮水后1h尿和随意尿最有相关性。γ=0.7238,所以尿蛋白检测可取随意尿标本。应用随意尿标本,检测了各型肾病、尿路感染、高血压、Ⅱ型糖尿病及SLE患者尿内的β₂-MG,ALb、IgG和THP含量,认为尿中4种蛋白的检测对判断肾功能的受损程度和损伤部位优于BUN和肌酐（血Cr）。更多还原

【Abstract】 Using RIA method,we took 4 kinds of urine specimen from 100 normal persons which were taken in the morning 1h after drinking,voluntary and all- 24h,and stored at two temperature 4 C and -30℃。In order to detect the concentration of the urine protein β₂-MG,ALb,IgG and THP。So as to compare the relativity between them,as well as for t-test.The results are as follows:for 3-days-storage at 4 C and 2-weeks-storage at -30℃,P>0.05;for the ALb,IgG and THP between voluntary urine and 24h urine,r=0.7565,0.7865 and 0.7537 respectivcly;for β₂-MG,between the 1h-urine after drinking and voluntary urine,r=0。7238.In this article we measured the urinary levels of β₂-MG,ALb,IgG and THP with voluntary urine specimen in 177 cases of various typies of nephropathy,urino-infection,and diabetic nephrosis,hypertesion-nephro-sis,systemic lupus erythematosus.With this work,we think the method of testing urine protein with voluntary urine specimen is not only accurate for collecting but also convenient for the patient.It is more accurate and sensitive than the traditional BUN and Cr for the appreciation of kidney function damage.And it is gives a early stage index of kidney damage.更多还原