【摘要】 本文研究了藏药浴前后类风湿性关节炎（RA）的免疫功能变化。RA患者藏药浴前类风湿因子（RF）滴度,免疫球蛋白（Ig）G.M.A及CD₄细胞水平较高,但CD₈细胞水平却显著低下。临床资料表明,藏药浴对RA的有效率达94.3％。为了阐明藏药浴治疗RA的机理,我们测定了藏药浴前后的RF滴度;Ig水平;补体C₃;₃H—TdR掺入淋巴细胞转化及CD₈.CD₄.CD₈细胞水平。结果表明:藏药浴后RF滴度下降和转阴者共达70.6%;Ig水平显著降低;CD₄细胞数下降而CD₈细胞水平上升;₃H—TdR淋巴细胞转化刺激指数（SI）明显下降。这提示,RA患者未经藏药浴处理时,其淋巴细胞培养上清液中可能有高浓度的白细胞介素—2促进因子（IL₂—EF）。我们认为藏药浴可通过提高RA的CD₈细胞和降低CD₄细胞水平而达到对该病的免疫调整作用。更多还原

【Abstract】 In present paper, Rheumatoid Arthritis （RA） was studied before and after treated with Tibetan Medicinal Bathing（TMB） , RA patients showed a high level of Rheumatoid factor （RF）, Immunoglubulin （Ig） G, M, A, and CD₄ cells, but a low level of CD₈ cells before TMB treated. Clinical data showed that the efficacious rate of TMB on RA patients, the RF title, Ig level, Complement 3 （C₃） , ³H-TdR incorpration of lymphocytes and CD₃,CD₄,CD₈,level was detected. Results showed that the RF title reduced, and becoming negative in 70.6%of RA patients;Ig level also significantly re’duced CD₄ cells reduced and CD₈ cells increased relatively after TMB compared with control groups. As for ³H-TdR incorpration, the stimulation index （SI） was obviously reduc- ed after TMB. It suggested that there was a higher concentration of Interleukin 2 enhancing factor （IL2-EF） involving in lymphocyte culture of RA patients. The results metioned above suggested that the TMB showed a immunomodulating effects on RA patients through increasing the level of CD₈ cells and reducing CD₄ cells.更多还原