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外周血淋巴细胞微核出现率与癌肿的关系

THE RELATION BETWEEN THE APPEARANCE RATE OF MICRONUCLEI IN THE BLOOD AND CANCERS

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【作者】 王心龙徐邦生佘耀南张晓萍金星进杨鸿君

【Author】 Wang Xinlong Department of Histology and Embryology,Nantong Medical College

【机构】 南通医学院组织胚胎学教研室南通市妇产科医院

【摘要】 由静脉采集癌肿病患者、非癌肿病患者和体检健康者的外周血各2ml,用明胶浓集法分离淋巴细胞,以微核测定法检测上述3组外周血淋巴细胞中的微核出现率。结果:健康对照组为0.75‰,非癌肿病组为6.67‰,癌肿病组为22.03‰;表明癌肿组的微核出现率,明显高于非癌肿病组和健康对照组(P<0.01)。且非癌肿病组也高于健康对照组(P<0.01)。说明外周血淋巴细胞微核出现率的多寡,可以预测病变,检测癌肿,在临床上有一定参考价值。

【Abstract】 Authors take blood from the patients with cancers and with non-cancersand the health persons in 2 ml respectively,collect the lymphocyte by meansof cell fractionation method,and check the appearance rate of micronueleiin the blood.The rates are 0.75% for the health persons,6.67% for thepatients with non-cancers and 22.03% for the patients with of cancers.Thisresult shows that the rate in the cancer group is higher than in the non-cancer group and the health group(p<0.01).It is higher in the non-cancergroup than in the health group(p<0.01).Therefore cancer may be forecastedthrough examining the rate.

【关键词】 微核淋巴细胞外周血
【Key words】 micronucleilymphocytebloodcancer
  • 【文献出处】 南通大学学报(医学版) ,Journal of Nantong University(Medical Sciences) , 编辑部邮箱 ,1992年01期
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