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肌肉CT扫描对神经肌病的研究

Study of Neuromuscular Diseases on CT Scan

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【摘要】 肌源性肌病和神经源性肌病CT共同特征为肌块体积缩小、间隙增宽、密度减低。前者如多发性肌炎、假肥大型肌营养不良症在肌萎缩前早期出现密度降低;呈点状、条索状、蜂窝状、蚕蚀状、最终呈均片状低密区。后者如运动神经元疾病、周围神经病,先有肌萎缩,密度减低较迟,因病因与损害部位不同,除腓骨肌萎缩症外,常不规則,不对称。后期均有相似密度改变。病理证实密度减低乃纤维脂肪组织浸润所致。

【Abstract】 The common characteristics of myopathic and neuropathic muscular diseases on CT scan are reduction of muscle mass, widening of space between individual muscles and decreased muscle density. The former group, including polymyositis and Duchenne’s muscular dystrophy, shows early decrease of muscle density revealing patch, stripped, moth-eaten and washed-out or fuzzy decrease of density. The latter group, including motor neuron disease and peripheral nerve disease,shows early reduction of muscle mass before decrease of muscle density. In most of the neural diseases (except Charcot-Marie -Tooth peroneal muscular atrophy), there is irregular and asymmetric decrease of muscle density. In severer cases, myopathic and neurophathic diseases may have similar changes. Biopsy reveals that the change is caused by localized replacement of muscle tissue by fats and/or connective tissue.

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