【摘要】 采用改良的Eriksson法。分析55例麻风（TT型15例,界线类30例,LL型10例）及60例健康人血清中的α₁抗胰蛋白酶抑制活力（α₁—AT）。结果TT型的α₁—AT为1.18±0.15mg/ml,同正常人比较差异不显著（p>0.05）;界线类为1.02±0.28mg/ml,同正常人比较差异非常显著（p>0.01）;LL型为0.78±0.42mg/ml,也明显低于正常人（p<0.01）。α₁—AT均值从TT端移行至LL端时呈逐渐下降趋势。α₁—AT缺乏在麻风的发病中可能起一定作用。推测用纯化的α₁—AT或提高α₁—AT产生的制剂可能对麻风的治疗有益。更多还原

【Abstract】 Inhibitory activity of α₁ antipepsin （α₁—AT） in the sera was determined with modified Eriksson method in 55 leprosy patients （TT 15. B group 30 and LL 10） and 60 healthy persons as control. The results showed that the α₁—AT level is 1.18±0.15mg/ml in TT without significant difference （p>0.05）, and 1.02±0.28mg/ml and 0.78±0.42mg/ml in B group and in LL with highly significant difference （p<0.01） respectively, as compared with control. Th mean of α₁ —AT levels showed a tendency to decrease from TT to LL. The authors think that lack of α₁—AT might play some role in pathogenesis of leprosy and purified α₁—AT or its preparation being able to promote the produce of α₁—AT might be useful in treatment of leprosy.更多还原