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胃粘膜肠上皮化生CEA单克隆抗体免疫组化的研究
The immunohistochemical study of CEA monoclonal antibody for epithelial metaplasia of mucous membrane of stomach
【摘要】 胃粘膜肠上皮化生(简称肠化)的分型标准以及与胃癌的关系尚不统一,目前仍有争议。长期以来,国内外不少学者研究肠化与胃癌的关系,较多运用的是H.E染色、粘液组化染色及电镜技术手段,而应用免疫组化技术研究肠上皮中癌胚抗原(Carcinoembryoncantigen,简称CEA)尚属少见。本文试图通过上述方法,探讨肠化与胃癌的发生关系。
【Abstract】 The classfied criteria for intestinal epithelial metaplasia of mucous membrane of stomach and the relations of the criteria with stomach cancer have not been unified, with some dis- putes. Recently internal and external scholars classified intestinal metaplasia as different sub- varieties based on immunohistochemical method to study the relations of intestinal metaplasia with stomach cancer. We adopted CEA monoclonal antibody immunohistochemical stain for CEA of stomach cancer and various intestinal metaplasia to examine the distribution of CEA in these tissues and make an inquiry into the relations of intestinal metaplasia with stomach cancer.
【Key words】 carcinoembryonic antigen (CEA); CEA monoclonal antibody; intestinal epithelial metaplasia; stomach cancer;
- 【文献出处】 佳木斯医学院学报 , 编辑部邮箱 ,1992年03期
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