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香菇多糖药理作用的实验研究

Experimental Study on the Pharmacological Effect of Lentinan

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【作者】 胡苏林齐建华

【Author】 Hu Sulin Qi Jianhua (Department of Pharmacology, Jiangxi Medical College) Doctoral Studenl of Second Shanghai Medical University at present

【机构】 江西医学院药理学教研室上海第二医科大学 博士研究生

【摘要】 将30只小鼠随机分成3组,每组10只,分别用香菇多糖60 mg/kg、30 mg/kg 和生理盐水口服,每日一次。连续8 d 给药后1h 实验发现香菇多糖60 mg/kg 口服给药能显著提高小鼠的抗疲劳和耐缺氧能力,而30 mg/kg 及60 mg/kg 口服给药均能明显提高小鼠对电信号剌激的反应能力,有助于增强学习记忆力。提示,香菇多糖具有明显的抗衰老,增强体质,促进智能发育的效应。

【Abstract】 Thirty mice were divided into 3 groups at random,with each group contaning 10 mice.Oral ad- ministration of Lentinan,extract from Lentinus edodes(Berk)Sing,60 mg/kgand 30 mg/kg was giv- en separately to 2 groups for 8 days,the third group was given normal saline for control.Our study demonstrated that Lentinan of 60 mg/kg orally could increase the capability of fatigue endurance and antianoxia in mice,and that of 30 mg/kg and 60 mg/kg could significantly increase the reactivity of electric signal stimulate.It is suggested that Lentinan may improve the effect of learning and memory. Its mechanism remains to be studied.

  • 【文献出处】 江西医学院学报 ,Acta Academiae Medicinae Jiangxi , 编辑部邮箱 ,1992年04期
  • 【分类号】R965.4
  • 【被引频次】7
  • 【下载频次】134
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