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髂内动脉灌注抗癌药物治疗晚期妇科恶性肿瘤

TREATMENT OF ADVANCED GYNECOLOGIC MALIGNANCIES BY INTRA-INTERNAL ILIAC ARTERIAL INFUSION OF ANTI-CANCEROUS AGENTS

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【作者】 李芮宗李智岗孟祥文贾志强王澎马自新

【Author】 Li Rui~zong, et al. Department of Radiology The Second Affiliated Hospital of Shanxi Medical College

【机构】 山西疗学院第二医院放射科河北医学院第四医院放射科山西疗学院第二医院放射科 030001030001

【摘要】 本文报道经病理证实的24例晚期妇科恶性肿瘤髂内动脉造影表现及灌注治疗的结果。24例中卵巢癌5例,宫颈癌18例,宫体绒癌1例。治疗前常规行双侧髂血管造影,抗癌药物用顺铂(50~80mg/m~2)和丝裂霉素(8~10mg/m~2),每2~3周灌注一次,3~5次为一个疗程。治疗结果为盆腔肿块和局部病灶缩小50%以上者19例,缩小但不足50%者4例,病灶无明显变化者1例。作者认为,盆腔动脉造影对妇科恶性肿瘤的诊断具有重要意义,髂内动脉灌注对晚期妇科肿瘤是一种有效的治疗措施,并能减轻化疗副作用。

【Abstract】 This aritcle reported the angiographic appearances and the therapeutic results in 24 pathologic proved cases advanced gynecologic malignancies treared by intrainternal iliac arterial infusion, including 5 ovarin carcidomas, 18 cervical carcinomas, and 1 chorioepethelioma.The bilaterial iliac arteriography was performed beforehand and followed by the arterial infusion.The doses of anti-cancerous agents were CDDP 50~80mg/m~2, MMC 8~10mg/ m~2.The treatment was performed every two to three weeks with three to five times for one course.The results of treatment showed that the tumor diminution in size over 50% was noted in 19 cases, lower than 50% in 4 cases, whereas 1 case showed no change.After all the an giography of iliac artery was significant for the diagnosis of gynecologic malignancies while transcatheter infusion chemotherapy was also an effective measure for the treatment with comparative decrease in general side effects.

【关键词】 妇科肿瘤髂内动脉灌注法局部
【Key words】 Gynecologic tumorCarcinomaInternal iliac arteryInfusion
  • 【文献出处】 介入放射学杂志 ,Journal of Interventional Radiology , 编辑部邮箱 ,1992年01期
  • 【被引频次】6
  • 【下载频次】19
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