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可复性输精管经皮穿刺注射栓堵节育法有效性安全性的临床观察

Clinical study of safety and efficacy of percutaneous of polyurethane elastomer(MPU)plugs for vas occlusion.

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【作者】 陈振文谷翊群梁小薇吴志刚殷尔晶李鸿

【Author】 Chen Zhen-wen National Research Institute for Family Planning, Beijing, 100081.

【机构】 国家计划生育委员会科学技术研究所

【摘要】 53例MPU输精管栓堵术后2年的系统观察结果表明,术后12个月累积精子消失率为85%,术后18个月累积精子消失率为96.2%,迄今尚有2例精子仍未消失(3.8%)。术后近期并发症发生率为7.6%,远期并发症发生率为1.9%。提示:MPU输精管栓堵作为一种男性节育方法有效,但也存在因输精管损伤、阻塞所致术后近远期并发症。对MPU栓堵机理和栓堵剂的用量亦进行了讨论。

【Abstract】 The contraceptive efficacy of reversible vas occlusion by injection of medical-grade polyurethane (MPU) reported by Zhao Sheng-cai in 1988 was over 98 % and almost without long-term complications. The purpose of this study was to evaluate the safety and efficacy of MPU vas occlusion during 2 years follow- up of 53 cases in Beijing area. The results were as follows:azoospermia evidenced by semen analysis after centrifugation of the samples was achieved in 45 volunteers (85%) within 12 months after vas occlusion. Sperm disappeared in 51 (96.2%) volunteers within 18 months post vas occlusion and has not. Get disappeared in 2 cases (3.8%)up to now. Complications such as hematoma, hamospermia have been found in 1 and 3 cases respectively within 2 weeks, and spermatocele in 1 case in 2 years after operation. Spermatocele was assumed to be attributed to rupturing of the vas after injection of MPU. Much longer duration for achieving azoospermia in MPU occluded men and spermatocele occurred may be due to injection of the excessive volume of MPU.

  • 【文献出处】 中国计划生育学杂志 ,Chinese Journal of Family Planning , 编辑部邮箱 ,1992年02期
  • 【被引频次】2
  • 【下载频次】31
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