【摘要】 为寻找抗早孕有效的避孕药,合成了五个未见文献报道的双炔失碳酯类似物。本文报道了它们的合成方法及元素分析、质谱、红外、核磁共振等光谱数据。小白鼠初步药理试验表明化合物Ⅵ、Ⅶ、Ⅸ具有较好的抗早孕活性。更多还原

【Abstract】 In order to obtain effe-ctive anti—early pregnant contraceptives,five Anordrin anal.gs were synthesizedby esterification of anordiol,and theirchemical structure have been identifiedby EA,IR,Ms and ’HNMR.Some of themhave shown effective anti-early pregnantaction in mice.更多还原