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山苦茶的利胆作用和毒性

Choleretic Action and Toxicity of Mallotus furetianus

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【作者】 华运群陈小川吴永强颜毅韩洪徐生淦

【Author】 Hua Yunqun Chen Xiaochuan Wu Yongqiang Tutor:Xu Shenggan(Dept,of Surgery) (Dept.of Pharmacology,Hainan Medical College Haikou,570005)

【机构】 海南医学院药理学教研室海南医学院病理学教研室海南医学院外科学教研室海南医学院外科学教研室 海口570005海口570005

【摘要】 山苦茶是生长于海南省各地的一种茶饮料,本实验用其醇提物乳剂,于麻醉的大白鼠十二指肠注射0.1g·kg-1和0.2g·kg-1(相当生药0.562g·kg-1和1.124g·kg-1)有利胆作用。用其醇提物5g·kg-1(相当生药28.1g.kg-1)灌胃给药做急性毒性实验,未发现毒性表现及主要脏器的病理学变化。

【Abstract】 Mallotus furetianus(Baill.).Muell.Arg.,a kind of tea drinks,grows in all parts of Hainan province.The products extracted by alcohol from the herb was emulsionized for the experiment of choleretic action and acute toxicity in rats. The anesthetized rats injected in to the duodenum with the products of 0. 1g.kg-1or 0. 2g.kg-1 (corresponding to 0. 562g.kg-1and1.124g·kg-1of dry medicinal herbs respectively),was set under the observation on the.bile secretion with choledochostomy.The result suggests that the emulsionized products of furetianus possesses obvious choleretic action in rats The rats were given i.g.5g·kg-1products(corresponding to 28.1g.kg-1of dry medicinal herbs)for the acute toxicity tests.No toxic symptoms and pathologic changes of vital organs were seen,which indicated that alcohol—extracted furetianus was a practical non—toxic medicine.

【基金】 海南省自然科学基金资助课题
  • 【文献出处】 海南大学学报(自然科学版) ,Natural Science Journal of Hainan University , 编辑部邮箱 ,1992年04期
  • 【被引频次】19
  • 【下载频次】126
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