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选择性支气管动脉灌注化疗对晚期肺癌的疗效观察

Observation on the Effect of Selective Bronchial Artery Infusion Chemotherapy on Advanced Lung Cancer

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【作者】 莫谷良姚罗章刘日洪

【Author】 Mo Guliang, et al The First People’s Hospital of Changde, Hunan, 415003

【机构】 湖南省常德市第一人民医院湖南省常德市第一人民医院

【摘要】 对63例晚期肺癌患者进行136次选择性支气管动脉造影与灌注化疗,所用药物为PDD或ADM+MMC/5-Fu,总缓解率为30.1%,经6~23月回访49例死亡,14例生存,总的平均生存期6.5月,中位生存期5.2月,比较了肺癌类型、疗效及分期与生存期的关系,结果表明鳞癌可作为BA1治疗首选,病变分期对疗效影响不大,并对缓解期短的原因进行了讨论。

【Abstract】 Selective Bronchial Arteriography and Infusion(BAI) chemotherapy 136 times were successfully performed on 63 patients with advanced lung cancer. PDD or ADM with MMC/5-FU was used for infusion. Total remission rate was 30.1%. Of the 63 cases followed up, 49 cases died and 14 cases are still living with a mean survival time of 6.5 months and median survival time of 5.2 months. Comparing the survival time with the relationship between the type of cancer pathology, the therapeutic effects, and the stages of the disease we got, the results as follows: squamous cell carcinoma might be useo for the fir st BAI performance; the stage of disease had no great influence upon therapeutic effect. The causes of short remission time are discussed in the article.

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