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妊娠性滋养细胞疾病发病因素的分析

AN INVESTIGATION ON THE CAUSES OF GESTATIONAL TROPHOBLASTIC DISEASES

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【作者】 黄万珠赵恒毅古明华黎艾欣许进仇小强梁秋萍简梅芝叶健阮少芳白桦

【Author】 Huang Wanzhu;Zhao Hengyi;Gu Minghua Department of Gynecolog oncology.Guangxi Cancer Institute

【机构】 广西肿瘤研究所妇瘤科广西肿瘤研究所妇瘤科广西医学院卫生系统计学教研室广西区人民医院广西区妇幼保健院

【摘要】 省级三家医院1987年住院确诊滋养性细胞疾病患者:良性葡萄胎30例,恶葡30例,绒癌20例,进行患者的病因和流行病学调查,对照组选自同期住院的正常产妇。病例组与对照组按1∶2配对.结果:单因素 Logisitic 回归模型分析方法,选出22个有相对意义的因子。多因素分析:年龄、孕早期使用激素史、丈夫初婚年龄、初潮年龄、怀孕次数、停房事天数等,有显著意义(P均<0.05或<0.01).

【Abstract】 Gestational trophoblastic diseases were diagnosed in 1987 from three main hospitals of Guangxi.There were 30 cases of hydatidiform mole,30 cases of malignent mole and 20 cases of choriocar- cinema,The etiology and epidemiology of these diseases were investigated.Control groups were selected from normal postpartum women of the about three hospitals,who were indoor patients during the period of investigation.The ratio between the patient group and the control group was 1:2.The results were as follows:22 relatively significant factors were selected by single factore logistic regresion analysis method.Then,the following more related factors(P<0.05 or<0.01)were chosen by multiple-factors analysis,These factors are age,history of taking hormonal pills in the early stages of pregnancy,age of marriage of their husbands,age of menarche,number of pregnancies and the number of days of discontin- ued sexual intercourse before admitled to the hospitals.

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