【摘要】 观察了有机锗对黄曲霉毒素B₁（AFB₁）致肝癌作用和免疫功能的影响。结果表明,有机锗对AFB₁诱发的肝癌前病变酶变灶有显著的抑制效果,而对WBC吞噬率、ANAE及MII等免疫功能有显著的增强作用.提示有机锗具有抑制AFB₁的致癌作用,可能与其通过恢复或增强机体免疫功能有关。更多还原

【Abstract】 Organic germanium was investigated regarding its effects on aflatoxin B₁（AFB₁）—in- duced hepatocarcinogenesis and also on the immunological functions in rats.The results indicated that organic germanium had significant inhibitory effects on the aflatoxin B₁—induced hepatocarcinogenesis and also had marked enhancing effects on the immunological functions,such as increasing the phagocyto- sis of polymorphonuclear leucocytes,the migratory inhibition of leucocytes and the positive rate of acid-α- naphthyl acetate esterase.These results suggested that organic germanium can inhibit the hepatocarcino- genesis induced by AFB₁ and such effect may be associated with the restoring or strenythening of the im- munological functions of the rats.更多还原