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染色体畸变及微核估算事故受照者生物剂量的比较研究

COMPARISON OF ESTIMATION INDIVIDUAL BIOLOGICAL DOSE TO ACCIDENTAL RADIATION BY CHROMOSOME ABERRATIONS AND MICRONUCLEI

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【作者】 白玉书关树荣张秀霞

【Author】 Bai Yushu;Guan Shurong;Zhang Xiuxia Laboratory of Industrial Hygiene, Ministry of Public Health, Beijing 100058

【机构】 卫生部工业卫生实验所卫生部工业卫生实验所 北京 100088北京 100088北京 100088

【摘要】 用外周血淋巴细胞染色体畸变(双+环)和微核的剂量效应曲线估算了5例受60Co γ线事故照射病人的生物剂量。结果表明,在照后早期,用上述两种方法估算的剂量与物理剂量基本一致。尤其对较均匀照射的3例(A、B和E)“双十环”剂量与物理剂量相当吻合,同时发现,用微核率估算的剂量偏高。本文对上述结果进行了讨论。

【Abstract】 Biological doses of 5 cases exposed to 60Co γ-ray were estimated bythe curves of relationships between radiation dose and chromosome aberations and mi-cronuclei of periphcral blood lymphocytes. The results indicated that biological doseestimated by "dic. + r." and micronuclei were quite approximate to the physical dose atearly phase of post irradiation. Specially, in 3 cases of uniform doses. the doses esti-mated by "dic. + r." were nearly identical to the physical dose. At the same time, itwas showed that dose estimated by micronuclei were higher than those of "dic. + r."doses.

  • 【文献出处】 辐射研究与辐射工艺学报 ,Journal of Radiation Research and Radiation Processing , 编辑部邮箱 ,1992年04期
  • 【被引频次】13
  • 【下载频次】27
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