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191例患者外周血染色体核型分析
ANALYSIS OF CHROMOSOME KARYOTYPE IN 191 PATIENTS WITH VARIOUS CLINICAL CHARACTERICS
【摘要】 191例因流产、早产等原因做了外周血淋巴细胞培养和染色体制备。显帶后行镜下或显微摄影核型分析,发现染色体异常15例。其中,流产病例中发现额外小染色体3例;标记Y染色体3例。此两种异常均系遗传而来,在文献资料中较为少见。
【Abstract】 Chromosomal preparation were made from peripheral blood lymphocytes in 191 cases including abortion or stillbrith. The analysis of chromosome karyotype was carried out by G-banding teachniques in all cases and additionally by C-banding and siliver staining in some cases. The chromosome abnormalities were found in 15 cases, of which 3 showed additional small chromosome and 3 "marker" chromosome; all the 6 patients suffered from abortion. These abnormal chromosomes relate to heredity and are rare in the literature.
【关键词】 额外小染色体;
标记染色体;
家系谱;
外周血;
异常染色体;
核型;
【Key words】 additional small choomosome; "marker" chromosome; genealogy; chromosome karyotype;
【Key words】 additional small choomosome; "marker" chromosome; genealogy; chromosome karyotype;
- 【文献出处】 承德医学院学报 ,Journal of Chengde Medical College , 编辑部邮箱 ,1992年02期
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