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191例患者外周血染色体核型分析

ANALYSIS OF CHROMOSOME KARYOTYPE IN 191 PATIENTS WITH VARIOUS CLINICAL CHARACTERICS

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【作者】 李继秋石淑荣于仁民胡向明孙淑敏吴萍

【Author】 Li Jiqiu, (Laboratory of Engenic and Heredity, Clincal Medicine Institute)

【机构】 承德医学院临床医学研究所优生遗传研究室承德医学院临床医学研究所优生遗传研究室

【摘要】 191例因流产、早产等原因做了外周血淋巴细胞培养和染色体制备。显帶后行镜下或显微摄影核型分析,发现染色体异常15例。其中,流产病例中发现额外小染色体3例;标记Y染色体3例。此两种异常均系遗传而来,在文献资料中较为少见。

【Abstract】 Chromosomal preparation were made from peripheral blood lymphocytes in 191 cases including abortion or stillbrith. The analysis of chromosome karyotype was carried out by G-banding teachniques in all cases and additionally by C-banding and siliver staining in some cases. The chromosome abnormalities were found in 15 cases, of which 3 showed additional small chromosome and 3 "marker" chromosome; all the 6 patients suffered from abortion. These abnormal chromosomes relate to heredity and are rare in the literature.

  • 【文献出处】 承德医学院学报 ,Journal of Chengde Medical College , 编辑部邮箱 ,1992年02期
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