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原发性高血压病人外周血T淋巴细胞亚群的研究

SURVEY OF T CELL SUBPOPULATION IN PERIPHERAL BLOOD IN PATIENTS WITH ESSENTIAL HYPERTENSION

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【作者】 刘希英黄振学张强赵秀珍李玉香

【Author】 Liu Xiying, Huang Zhenxue, Zhang Qiang, et al Department of Microbiology

【机构】 青岛医学院微生物学教研室青岛医学院卫生学教研室青岛医学院诊断学教研室青岛医学院内科学教研室青岛医学院微生物学教研室 研究生

【摘要】 采用酶免疫法检测了80名原发性高血压病人外周血T淋巴细胞亚群.与对照组相比,CD3、CD8细胞减少,CD4/CD8比值升高;在高血压的不同病期,上述指标也有明显改变.结果表明,病人的免疫调控发生紊乱,免疫损伤可能是原发性高血压病因及病情进展的主要因素之一.

【Abstract】 The T cell subpopulation in peripheral blood in 80 patients with essential hypertension was determined by the immuno-en?yme assay. The result showed that the percentages of CD3 and CD8 cells were lower and CD4/CD8 ratio was higher in the patients than in the controls and that these indices varied obviously at different stages of hypertension. This indicates that there is a disorder of iummno-regulation in the patients with essential hypertension, and immunological injuny may be one of the important factors in the development and progress of the disease.

【关键词】 高血压T淋巴细胞
【Key words】 hypertensionT lymphocytes
  • 【被引频次】2
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