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肝素治疗肺心病的血液流变学观察

HEMORHEOLOGICAL OBSERVATION OF CHRONIC COR PULMONALE TREATED WITH HEPARIN

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【作者】 程兆忠于淑美张盛珍

【Author】 Cheng Zhaozhong, Yu Shumei, Zhang Shengzhen Department of Diagnostics

【机构】 青岛医学院诊断学教研室青岛市立医院青岛市立医院

【摘要】 对35例慢性肺源性心脏病病人进行了部分血液流变学参数的测定.对部分病人用小剂量肝素(50~100mg/d)治疗.结果表明,肺心病组的全血比粘度、血浆比粘度、红细胞压积均明显高于正常对照组(P<0.01);肝素有降低全血比粘度和红细胞压积的作用.提示血液流变学在肺心病发病及诊断和治疗中有一定意义.肝素可作为肺心病综合治疗措施之一.

【Abstract】 Some hemorheological parameters were determined in 35 patients with chronic cor pulmonale. Eight of the patients were treated with Heparin in a dosage of 50-100mg/d by intravenous infusion. The result showed that the values of the whole blood viscosity, the plasma viscosity and the hematoerit in the Patients were significantly higher than normal (P<0.01) and that the levels of the whole blood viscosity and the hematoerit decreased as the disease was being treated with Heparin. The above result indicates that blood rheology plays a role of significance in development, diagnosis and treatment of chronic cor pulmonale and that Heparin might be helpful in the multiple-treatment of the disease.

【关键词】 肺心病血液流变学肝素
【Key words】 pulmonary heart diseasehemorheologyheparin
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