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牛磺酸与心脏及其疾病的研究进展

RECENT ADVANCES IN STUDY OF TAURINE AND CARDIOLOGY

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【作者】 张宏来蒋滢

【Author】 Zhang Honglai Jiang Ying (Dept. of Biochemistry, Suzhou Medical College Sozhou 215007, China)

【机构】 苏州医学院生化教研室苏州医学院生化教研室

【摘要】 <正> 牛磺酸(Taurine,Tau.2-氨基乙磺酸)为体内一种β-氨基酸,属于非蛋白质氨基酸。主要分布在兴奋性较高的组织如神经系统、肌肉组织、视网膜及血小板中。近年来研究认为牛磺酸不仅参与合成胆汁酸、调节渗透压、阻断神经冲动的功能,还有抗氧化及维持膜稳定性等方面作用。自从

【Abstract】 Taurine is a ubiguitious amino acid in the animal kingdom. Tt is found widely throughout the body and in particularly high concentrations in heart. Availbale evidence implies that taurine may serve a homestatic founction in heart by stablizing membrane through the regulation of cell membrane permeability to ions.Taurine influance K+, Cl- and Ca2+ translocation in heart. Recently, taurine was found that it may inhabit the membrane protein phsophloration involved Ca CaM system.Taurine is higher than noral ammounts in states of cardiovascular pathology; i.e. congestive heart failure and hypertension in men. Taurine can also protect the heart from drug-induced acute damage.

【关键词】 TaurineHeartCell membraneCa2+
【Key words】 TaurineHeartCell membraneCa2+
  • 【被引频次】15
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