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健胃愈疡片治疗消化性溃疡的临床研究

Clinical Studies on the Treatment of Peptic Ulcer with Jian-Wei Yu-Yang Tablets(健胃愈疡片)

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【作者】 李家邦; 金益强; 陈国林; 赵玉秋; 潘其民; 刘桢祥; 曹光复; 罗衡宝; 金如寿; 黄德纯; 旷祝华; 邹钢辉;

【Author】 Li Jia-bang Jin Yi-qiang The Institute of Integrated Traditional Chinese and Western Medicine,Hunan Medical University,Changsha(410008)

【机构】 湖南医科大学中西医结合研究所; 健胃愈疡片临床研究协作组; 健胃愈疡片临床研究协作组 长沙 410008; 长沙 410008;

【摘要】 本文报告健胃愈疡片治疗消化性溃疡二期临床试验结果,健胃愈疡片组354例,治愈率62.4%,总有效率93.8%,雷尼替丁对照组140例,治愈率50.7%,总有效率86.4%,两组比较,P<0.01,显示健胃愈疡片组疗效明显优于雷尼替丁对照组,且复发率低,无副作用。

【Abstract】 This article reports the results of second stage clinical trial on the treatment of peptic ulcer with Jian-Wei Yu-Yang(JWYY)tablets in comparison with a control group treated with ranitidine.The results showed that the cure rate for JWYY tablet group was 62.4% and its effective rate was 93. 8% in 354 cases,whereas the cure rate of the control group was 50.7% and its effective rate was 86. 4% in 140 cases.The differences between these two groups were hig(?)y significant(P<0.01).Based on syndrome differentiation,optimal effect was reached in treating liver stagnation and spleen deficiency syndrome and disharmony of liver and stomach syndrome. After one year follow up studies of the therapeutic effect,the recurrence rate of the JWYY tablet group was 17.7%,while that of the ranitidine group was 54.1%.In addition,JWYY tablet had no side-effects.These data indicated that JWYY tablets were a more effective therapeutic remedy for peptic ulcer.

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