【摘要】 <正> 雌激素受体(ER)和孕激素受体(PgR)的检测已广泛应用于临床。本文用ABC法(Avidin-BiotinComplex method)标记了75例乳腺癌石蜡切片,并结合临床资料对标记结果进行分析,旨在探讨ER、PgR免疫组化测定的临床意义。更多还原

【Abstract】 The ABC immunohistochemical method was performed on paraffin sections of 75cases of human breast cancers to detect ER and PgR. 44(58. 7%) of all cancers examinedwere ER-positive and 22(29.3%) were PgR-positive. There were more ER-positivesamples among the patients over 50 years old than those under 50 years old, P<0.05.There were more ER-positive samples in well-differentiated carcinomas than in poor-differentiated carcinomas,P<0. 05,and the patients with mucinous carcinoma, infiltra-ting Iobular carcinoma and papillary carcinoma had more higher ER levels than theothers. 36 at five years and 20 at ten years of all 44 ER-positive patients had survivedcompared to 16 and 5 of all 31 ER-negative patients respectively, difference of survivalrate between ER(+) and ER(-) groups were significant, P<0 .01.更多还原