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脾虚小鼠模型及健脾中药治疗的形态药理学研究

Mice’s Model of PI Difficiency and Its Study of Morphological Pharmacology after Treatment by Taking Medicine for Invigorating the "PI

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【作者】 许长照马永华卞慧敏张瑜瑶朱宏王耿

【Author】 Xu Changzhao, Ma yonghua et al (Nanjing College of TCM, Nanjing210029)

【机构】 南京中医学院南京中医学院 南京 210029南京 210029南京 210029

【摘要】 对饮食失节型脾虚小鼠模型及用四君子汤和祁白术对其治疗后与正常对照组、自然恢复组进行全身各系统的形态学观察比较,结果:脾虚组具有以消化系统为主的特定病变,其他系统也有涉及,以呼吸、生殖、免疫、内分泌等系统影响较大,四君子汤和祁白术对此脾虚证有显著的促复健作用。

【Abstract】 Mice’s model of "PI" deficiency syndrome (PDS脾虚证) caused by irregular eating was established and the mouse with PDS were treated by using Si Jun Zi Tang (SJZT四子汤君) and Qi Bai Su (QBS祁白术, Atractylodes Macrocephala Koidz ). Then comparison with control group and natural cure group were observed in patho morphology of the all systems and organs.Result: PDS group revealed the specific pathological changes in digestive system taking as main aspect, and other systems were also involved, such as respiratory, reproductive, immune, endocrine system etc. Those pathological changes due to different degrees of PDS were based on blood stasis, hemorrhage, transfer between solid and hollow organs in combination with other symptoms and signs. After PDS group treating by SJZT and QBS could be recovered rapidly and resulted better effects than natural cure group in morphological pharmacology.

  • 【文献出处】 中药药理与临床 ,Pharmacology and Clinics of Chinese Materia Medica , 编辑部邮箱 ,1991年05期
  • 【被引频次】16
  • 【下载频次】118
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