【摘要】 从中药五倍子中提取的鞣酸50和100μg/ml可显著地对抗TPA 100ng/ml引起的人白细胞DNA的损伤,30和50μg/ml可有效地对抗香烟烟雾凝聚物（CSC）400μg/ml引起的人白细胞DNA断链;鞣酸5μg/ml可明显对抗VB₂+光产生的O₂^-,但鞣酸浓度需增至80μg/ml才能明显对抗CSC产生的O₂^-。此外,鞣酸5μg/ml可显著对抗H₂O₂引起的红细胞膜脂质过氧化作用,此对抗作用随鞣酸剂量加大而渐明显。更多还原

【Abstract】 Tannic acid was extracted from Rhus chinensis Mill. At a concentration of 50μg/ml it could significantly prevent the DNA damaging effects induced by TPA (100 ng/ml) or cigarette smoke condensate (400 ng/ml). At concentrations of 5 ng/ml and 80 ng/ml, it could effectively scavenge the O 7 produced by VB2+hv and cigarette smoke condensate, respectively.The lipid peroxidation of red cell membrane induced by H2O2 was decreased significantly by tannic acid at a concentration of 5μg/ml.更多还原