【摘要】 本文对某PVC厂生活区空气VC污染状况及人群健康效应进行了调查,结果表明:空气质量指数（I₁）>1.50,空气质量属中度污染,此时氯乙烯（VC）≥0.17mg/m³,10～14岁儿童血清溶菌酶（S-LZM）活性明显增高（12.34μg/ml,萤光法）;而成人的S-LZM活性也增高（15.31μg/ml,比浊法）,且T细胞转化率明显降低（72.9％）,人群出现免疫效应;VC>4.0mg/m³（I₁>2.0）,空气质量属极重污染,成人染色体总断裂率明显增高（5.6％、G显带）,呈现细胞遗传毒性;VC>25.0mg/m³时,SCEs达9.08。并且发现效应有随接触VC量的增加而加重的趋势。研究还证明:I法评价空气环境质量比较合理,G显带染色体分析术对致突变物的环境流行病学调查有实用性。更多还原

【Abstract】 The monitoring results showed that the air Quality Index （I₁>1.50） and the air was at mid- dle pollution level when the air vinyl chloride （VC） concentration was≥0.17mg/m³. The serum lysozyme （S-LZM） activity of children aged 10 to 14 was 12.34ug/ml by fluorescence assay, and of the adult living in was （15.31ug/ml by turbidimetry） the area The T-cell transformation rate of the ad- ult （72%） were also found decreased significantly At this air pollution level, the immune effects ca- used by pollution could be detected. When VC was 4.0mg/m³ （I₁>2.0）, the air quality was at extre- me pollution level and the total chromosome brea- kage rates of the adult （15.6% G-banding） increased significantly, in which, the VC toxic effect on ce- llular heritage could be observed. When air VC was >25.0mg/m³, the sister chromosome exchanges of the adult increased to 9.08. The study also sugges- tes that the air quality evaluated with I method was comparatively suitable and the chromosome G- banding analysis is availbe on environment epidem icological survey.更多还原