【摘要】 本文将33例脑膜瘤的 ER、PR 测定结果结合临床、病理资料作了分析。发现 PR 含量与病人年龄、性别、月经状况、肿瘤大小以及有无 CT 脑水肿无关。术前应用糖皮质激素组其 PR 含量明显低于未应用组。上皮型肿瘤的 PR 含量高于纤维型。PR 含量高的肿瘤其均匀型核的出现率较高,提示 PR 大概能激活染色质部分。更多还原

【Abstract】 ER and PR were assayed in 33 meningiomasand the results were related with clinical andpathological materials.PR was predominantin meningioma and may be independent systemwhich is not regulated via estrogen-ER.No correla-tion of PR concentration with age,sex andmenopausal status of patients,or with tumor sizeand peritumor edema on CT scans was observed.But progesterone level in plasma was corelatedwith the level of PRc.The concentration of PRwas lower in tumors from glucocorticoid treatedpatients than in tumors from untreated subjects.PRlevel in meningothelial type was higher than itin fibrous type.Most of the tumors with higherlevel of PR were those with more homogeneousnucleus.It is reasonable to think that PR mayactivate the chromatin of the nucleus更多还原