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铅作业工人肾功能的调查研究

Investigation on Renal Functions of Workers Exposed to Lead

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【摘要】 对139名铅作业工人和51名无职业性铅接触史的城市居民进行调查。结果:铅作业工人尿肌酐(Cr)排出减少,血Cr含量增加,血中尿素氨含量增加,溶菌酶(Lys)含量减少。尿cr与尿ALA呈显著负相关,尿Lys与ALA呈显著正相关。尿Lys和血Cr含量在铅接触工人中存在明显的性别差异。表明职业性铅接触可引起肾脏损害,且存在明显的性别差异。

【Abstract】 139 lead-exposed workers and 51 non-exposed healthy persons as con-trols were investigated.Results showed that urine lead,ALA,BUN andglucose were increased in the exposed workers,and serun creatinine (Cr)was increased as a result of decreased urine Cr clearance.Urine lysozyme(Lys) and ALAD were also found to be increased.There was a nagative cor-relation between urine Cr and ALA and a positive correlation between urineLys and ALA.There was significant difference in blood Cr & urineLys be-tween men & women.It is suggested that occupational lead exposure can in-duce nephropathy which exist sex difference.

【关键词】 铅作业铅中毒肾损害溶菌酶
【Key words】 Lead-exposedLead intoxicationRenal lesionLysozyme
  • 【文献出处】 中华劳动卫生职业病杂志 ,Chinese Journal of Industrial Hygiene and Occupational Diseases , 编辑部邮箱 ,1991年05期
  • 【被引频次】10
  • 【下载频次】26
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