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急性脑卒中时脑脊液酶学改变(附108例分析)
Enzyme level change in cerebrospinel fuild of 108 patients with acute stroke
【摘要】 本文研究108例急性脑卒中患者乳酸脱氢酶(LDH),碱性磷酸酶(ALP);谷丙转氨酶(ALT),(γ—谷氨酸转肽酶)(r—GT),磷酸激酶(CPK),天门冬氨酸转氨酶(ASAT)血清及脑脊液检测。其中出血性卒中50例,缺血性卒中58例;男性74例,女性34例。年龄59~72岁,平均64.38岁。结果血清酶谱与脑脊液酶谱间无相关性,血清酶谱在急性脑卒中间及与对照组间比较无显著差异(P<0.05);出血性卒中CSF—LDH 值较缺血性卒中及较对照组为显著与非常显著升高(P<0.05或0.01);出血性卒中CSF—CPK 及CSF—ASAT 均非常显著升高(P<0.01),出血性卒中死亡组较存活组亦显著升高(P<0.05)CSF—γ—GT 值无显著改变(P>0.05)。我们认为CSF—LDH 值可作为鉴别出血性卒中与缺血性卒中的指标之一;急性脑卒中CSF—CPK 和CSF—ASAT 值均非常显著升高,而且可以预测出血性卒中的转归。
【Abstract】 We reviwed 108 patients withacute stroke(34 women,74 men,aged range 59-72 with a mean of64.38years)who admitted to the hos-pital between June 1986 to decem-ber 1890 This paper examined theconcen.rations of LDH,ALP,ALT,V GT,CPK and ASAT in the ce-rebrospinalic and sero-enzyme of50 patients with cerebrol hemorr-hage and 58 patients with cerebrolinrebrol infarctionx 24 hours afterthe onset of the vascular eventand in a control group of 31 patients.There was no correlation between the stroke group and the control group with CSF enzyme andthe sero enzyme(p>0.05).we foundsignificantly higher and highly coneentrationsof CSE-LDH,CSE-CPKand CSE-ASAT in the hemorrhagic stroke than ttvose ln ischemic stroke and the control group(P<0.05 or 0.01).Among the hemorrhagic strokepatients,we found a signficantlyCSF CPK and CSE-ASAT conce-ntrationsin those with diet patie-nts group than thrf in those withsurvivor.Uur study offers a supplement-ary examination for diagnosing,hemorragc stroke of ischemic str-oke during the early stage of thee(?)ent,with the possibilty of disti-nguishing which recognize patientswith poor prognosis from hemor-rhagic stroke durlng the early st-age affer onset of the event.
- 【文献出处】 综合临床医学 ,Clinical Medicine of China , 编辑部邮箱 ,1991年03期
- 【被引频次】1
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