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针灸对免疫调整作用的机理研究

A Study on the Mechanism of the Immunoactivity Affected by the Acupuncture

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【作者】 成柏华; 张开齐; 王如瑶; 李丽;

【Author】 Cheng Baihua

【机构】 上海第二医科大学传统医学研究中心针灸研究室;

【摘要】 <正> 针灸在临床上的疗效,很多涉及机体的免疫功能的改变,而针灸对免疫功能上的调节机理鲜为人知。作者在1986年曾提出针灸很可能通过针刺介质-内源性阿片肽的释放调整免疫功能的机理,该文已提示在针刺家兔"内关"穴从中枢到外周的同步观察中可见在尾核、海马、丘脑有亮脑啡肽(LEK)含量的增高,在外周有垂体及血浆内的LEK增高,而肾上腺髓质内的LEK则在针刺后下降,提示了在针刺过程中在不同脑区以及垂体等组织有阿片样肽的合成或释放增加,而肾上腺體质很可能是血液中LEK的直接来源。上述实验结果

【Abstract】 The effect of Acupuncture on the immunoacti- vity was further studied. The results showed that there were an increased levels of Leu-enkephalin in caudate nucleus, hippothalamus, thalamus, pituitary and blood plasma, a decreased level of Leu-enkepha- lin in adrenal medulla after acupuncture. It may be related with the analgesia and the modulation of the immunoactivity. Both Met-enkephalin and Leu- enkephalin could enhance the immunoactivity of B lymphocytes significantly, but there were no effects on T lymphocytes. The Leu-enkephalin and β-endo- rphin could enhance the activities of macrophage and could be blocked by Naloxon significantly. It means that the opioid receptor is involved in the mechanism. Both the Leu-enkephalin and Met-enke- phalin enhanced" the effect of N. K. activity but the β-endorphin was no significance. And the Nalo- xon also could block the enhancement effects.

  • 【文献出处】 中国针灸 ,Chinese Acupuncture & Moxibustion , 编辑部邮箱 ,1991年05期
  • 【被引频次】34
  • 【下载频次】122
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