【摘要】 本项研究用克山病病区与非病区粮喂养大鼠14周,做⁵⁴Mn示踪代谢实验,观察2日和7日时血液、心、肝、脾、肾、肌肉和骨骼对⁵⁴Mn（MnCl₂）吸收、分布以及从粪、尿中排除情况。结果表明,克山病病区组大鼠各种组织脏器对⁵⁴Mn 的吸收率普遍低于非病区组,其中以血液、肝、脾、肾、肌肉差异尤为显著,而粪尿中⁵⁴Mn 排除则明显高于非病区组。证实克山病病区粮可引起机体锰代谢的改变。我们认为克山病病区粮中高锰对发病的作用值得深入探讨。更多还原

【Abstract】 Two groups of Wistar rats were fed crops from endemic and nonendemic areas of Keshan disease respectively for 14 weeks,and then ⁵⁴Mn tracer metabolismof the animals was studied.The absorption of ⁵⁴Mn in all specimen of the rats inendemic group was lower than nonendemic group.The elimination of ⁵⁴Mn infeces and urine of the rats in endemic group was much higher than nonendemicgroup.The fact proved that crops from endemic areas of Keshan disease inducedMn metabolic change.更多还原