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麻风胶乳凝集试验检测抗酚糖脂抗体结果的报告

DECTETION OF ANTI-PG-1 ANTIBODY IN MB LEPROSY WITH GLETIN PARTICLE AGGLUTININ TEST

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【作者】 马家驹; 邓云山; 李绪文; 肖金平; 魏安德; 龙青文; 张锡宝; 孟梅白;

【Author】 Ma JaJu, et al. Leprosy hospital, hanzhong, Shaanxi

【机构】 陕西省汉中疗养院; 西安医科大学; 中国麻风防治研究中心; 中国麻风防治研究中心;

【摘要】 应用麻风胶乳凝集试验盒(MLPA)对59例现症多菌型麻风患者、17例治愈多菌型患者及47名健康人进行了抗酚糖脂抗体检测。其结果现症病例阳性率为95.06%,治愈者为17.65%,健康人均呈阴性。提示该试验有高度的特异性,可作为监测疗效、判定治愈的一种血清学检测方法。对25例现症患者的静脉和耳垂血清对照检测,结果一致。作者认为MCPA不需特殊设备,简单快速易行,是一种有潜力的麻风快速免疫检测方法,适用于实验室和现场检测。

【Abstract】 The gletin particcle agglution in test for the dectetion of anti-PG-1 antibody in MB leprosy showed that the positive rate was 96.05% in the active patients, and 17.65% in clinically cured patients, and 45 healthy persons were all negative. The results were encourtaging and suggested that the test is hightly sensitive, specific, simpple and rapid, and easy to perform in the field. The authors considered it is useful to the judgement of the effect of chemotherapy and might terve as a standard of cure. The more vein and coincident results of the sest with the use of blood specimens from both the the ear lobe. Beacause the test with the ear lobe blood is easier to do, it might be widely used in the field.

【关键词】 麻风; 凝集试验; 抗体;
【Key words】 Lepra Agglutination tests Antibodies;
【基金】 陕西省卫生厅医学重点科技项目
  • 【文献出处】 中国皮肤性病学杂志 ,The Chinese Journal of Dermatovenereology , 编辑部邮箱 ,1991年04期
  • 【下载频次】11
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