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急性前色素膜炎与HLA-B27抗原的相关性

The Association of HLA-B27 Antigen with Acute Anterior Uveitis

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【作者】 杨佩菲江之华富质洁沈晓莉吴若绮林丽芳

【Author】 Yang Peifei, et al Department of Ophthalmology, Fujian Provincial Hospital, Fuzhou

【机构】 福建省立医院眼科福建省心血管病研究所免疫室福建省心血管病研究所免疫室 福州 350001福州 350001福州 350001

【摘要】 对52例急性前色素膜炎患者,50例健康人,19例其他色素膜炎患者进行HLA-B27抗原的测定,结果急性前色素膜炎患者HLA-B27抗原阳性率为60%,正常对照组为2%,说明HLA-B27为急性前色素膜炎的相关抗原。HLA-B27阳性的急性前色素膜炎患者与HLA-B27阴性的急性前色素膜炎患者的临床现象是不同的。

【Abstract】 Using tissue typing technique (microcytotoxity assay), a particular MHC antigen HLA-B27 was examined in 52 patients with acute anterior uveitis (AAU), 50 healthy individuals and 19 cases of uveitis with other etiologies. The result showed that there wasa significant association of HLA-B27 in patients with AAU (60%), compared with the control (2%). It seems that an individual carrying the HLA-B27 is more likely to contract AAU, relative to an individual without this antigen. Further analysis also indicated that there were some differences between HLA-B27 positive AAU and HLA-B27 negative AAU based on their clinical features.

  • 【文献出处】 眼科研究 ,Chinese Ophthalmic Research , 编辑部邮箱 ,1991年02期
  • 【被引频次】3
  • 【下载频次】21
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