【摘要】 应用ELISA测定常见神经系统疾病的脑脊液CaM61例及血浆CaM40例,另以正常人的脑脊液17例及血浆13例作为对照组。发现15例脑梗塞脑脊液CaM平均值为3.15±1.15(X±SE),9例血浆CaM平均值5.24±1.50(X±SE);中枢神经系统感染16例胸脊液CaM为6.49±2.46(X±SE),12例血浆CaM为4.08±1.40(X±SE);中枢神经系统占位性病变19例脑脊液CaM为3.77±1.11(X±SE),11例血CaM为1.95±0.59(X±SE),各组与正常组比较,P值均为<0.05～0.01之间,61例脑脊液及40例血浆CaM含量经t检验,P>0.05,认为测定脑脊液及血浆的CaM具有同等的临床意义.作者指出中枢神经系统病变时可测脑脊液或血浆的CaM作为病情变化的客观指标之一。更多还原

【Abstract】 The CaM levels of CSF and plasma were measured in 61 CNSD patients and a control group of 17 healthy subjects.The normal values were 0.28±0.15 SE for CSF and 0.53±0.21 SE for plasma. In the CI group (n = 15), the CSF level of CaM was 3.15±1.15 SE, the plasma level 5.24±1.50 SE. In CNS infection group (n = 16), CSF CaM was 6.49±2.46 SE , plasma CaM 4.08 ± 1.40 SE. In the group of CNS occupying disorders ( n = 19 ), CSF CaM was 3.77 ±1.11 SE, Plasma CaM 1.95 ± 0.59 SE. t test revealed significant difference between each of the diseased groups and the control group ( P<0.05~0.01 ), but there was no difference between the CSF CaM levels and the corresponding plasma CaM levels ( P>0.05 ) .Thus the CSF and plasma levels of CaM are of equal clinical significance and therefore either of the two can be used as an index to monitor the varying conditions of CNS diseases.更多还原