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复方阿魏酸钠治疗脑血栓形成99例

Sodium ferulate compound in treating 99 patients with cerebral thrombosis

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【作者】 蒋雨平秦芝九苏美芳施裕森李威倪望云

【Author】 JIANG Yu-Ping, QING Zhi-Jiu, SU Mei-Fang (Department of Neurology, Huashan Hospital, Shanghai 200640) SHI Yu-Sen (The Eighth People’s Hospital, Shanghai 200233) LI Wei (The Ninth People’s Hospital, Shanghai 200011) NI Wang-Yun (Jiaxing First People’s Hospital, Jiaxing 314000)

【机构】 华山医院神经科上海第八人民医院上海第九人民医院嘉兴第一人民医院 上海 200040上海 200040200233200011314000

【摘要】 用双盲对照进行脑血栓形成临床试验。99例治疗组用复方阿魏酸钠胶囊,1颗tid共4wk,95例对照组用吡乙酰胺。总有效率分别为84%和28%,用评分记分法判断疗效时,表明复方阿魏酸钠使疾病改善和评分减少比对照组更明显,2组有显著性差异(P<0.05)。本药对血小板聚集功能有明显抑制(P<0.05),疗效肯定,无明显副作用。

【Abstract】 We used sodium ferulate compound, one capsule tid to treat cerebral thrombosis in 99 patients (M 68, F 31, age 64±12) for 4 wk and piracetam in 95 patients served as control in double blind method. The result showed that the total response rates were 84% and 28% respectively. An improvement of disease and a reduction of score in the treated group were significant in comparison with the control group (P<0.05), It had obvious inhibiting effect on platelet aggregation (P<0.05). No apparent side effects were observed.

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