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安非拉酮应用于单纯性肥胖症84例

Amfepramone in 84 patients with simple obesity

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【作者】 席先成周冰心张怡泰赵锦玲

【Author】 XI Xian-Cheng, ZHOU Bing-Xin , ZHANG Yi-Tai , ZHAO Jin-Ling (88th Hospital of PLA, Tai-an 271000) Weifang Second Pharmaceutical Factory, Weifang 261021 Weifang Medical College, Weifang 261021 Qingdao Medical College, Qingdao 266001

【机构】 中国人民解放军第88医院山东潍坊制药二厂潍坊医学院青岛医学院 泰安 271000潍坊 261021青岛 266001

【摘要】 安非拉酮化学名为二乙胺苯丙酮,为中枢性食欲抑制剂。据84例服25mg tid×2mo临床验证资料,本品治疗单纯性肥胖有效率为98%,治疗2mo平均降体重7.2±2.4kg,疗效高于对照组七消丸及文献报道的类似产品。本品对心、肝、肾及血象无不良反应。治疗期间注意低热量饮食以增加减肥效果。

【Abstract】 Amfepramone, (diethylpropion) is a central anorectic drug applied for reducing body weight in patients with simple obesity. Eighty-four patients with obesity were treated with amfepramone 25 rng tid for 2 mo, the response rate was 98%, 7.2±2.4 kg of body weight were lost. It was effective for reducing body weight than that of control group given Qixiao Wan. It had no adverse effects to heart, liver, kidney and blood cells. In order to enhance the clinical effects, low calorie controlled diets in the course of treatment is suggested.

【关键词】 安非拉酮食欲抑制剂肥胖
【Key words】 amfepramoneappetite depressantsobesity
  • 【被引频次】6
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