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三氮唑核苷治疗低血压休克期的流行性出血热23例

Ribavirin in the treatment of epidemic hemorrhagic fever in hypotensive shock stage in 23 patients

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【作者】 杜功舜艾黎明

【Author】 DU Gong-Shun, AI Li-Ming (The First People’s Hospital of Tianmen, Tianmen 431700)

【机构】 湖北省天门市第一人民医院湖北省天门市第一人民医院 天门 431700天门 431700

【摘要】 本组采用三氮唑核苷(病毒唑ribavirin)治疗流行性出血热低血压休克期的患者23例(男17例,女6例;年龄20-65yr,平均44±15yr),每日1g,疗程5d。结果:治疗组退热及血压稳定时间、少尿及多尿持续时间、尿蛋白消退及尿素氮(BUN)恢复正常时间均较对照组短(P<0.05),且未见明显副作用。

【Abstract】 Twenty-three patients (17M, 6F, age 20-65yr, 44±15yr) of hypotensive shock stage of epidemic hemorrhagic fever were treated with intravenous infusion of ribavirin 1g daily for 5 d. Nineteen patients served as control. The results showed that defervescence, to attain stable period of blood pressure, periods of oliguria and polyuria, disappearance of proteinuria and recovery of BUN to normal level were all significantly shorter than the control group, No serious adverse reactions were observed.

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