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银屑病血液流变学观察与探讨

AN OBSERVATION AND EXPLORATION OF HEMORHEOLOGICAL CHANGES OF PSORIASIS

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【作者】 王天慧邓丽丽吴鹏举王亚妹张德发齐明勤朱新辉吴锡熊丁龙芳陈辉

【Author】 Wang Tianhui et al Dept.of Dermatogy,Affiliated Hospital Wu Xixiong et al Dept. of Laboratory Techniques,Affiliated Hospital Shihezi Medical Colloge

【机构】 新疆石河子医学院附院皮肤科新疆石河子医学院附院检验科新疆石河子医学院附院检验科

【摘要】 本文对40例银屑病患者和40例健康人血液流变学八项指标进行了检测对照。患者全血比粘度、全血还原粘度、血浆比粘度、纤维蛋白原增高,血沉加快,血沉方程K值增大,均有显著性改变(P<0.05 或<0.001)。而红细胞压积和红细胞电泳时间无显著性差异。尚对50例银屑病治疗前后血液流变学指标进行配对比较,发现病情缓解后,红细胞压积、全血还原比粘度、纤维蛋白原改变有显著性差异(P<0.05)。

【Abstract】 This article reports the result of systematic observation of hemorheological changes of 40 cases of psoriasis in contrast with 40 healthy individuals. The results are as follows The patient whole blood specific viscosity, the whole blood reduction specific viscosity, plasma specific viscosity and fibrinogen becomes higher. Erythrocyte sedimentation speeds up and erythrocyte sedimentation equation k value increases. The changes are quite obvions (p < 0. 05 or <0. 001). But the hematokrit of the red blood cell and the time of electrophoresis have no obvious differ-ences. Before or after treatment of 50 cases of psoriasis to match and to compare among them, we found that after the patients relaxes the hematokrit of the red blood cell, the whole blood reduction specific viscosity and the fibrinogen change showed obvious differences (p <0. 05).

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