【摘要】 本文观察了放置含药宫内节育器(IUD)钥匙形(K-LNG-IUD,2号)、菱形(C-LNG-IUD,3号)、改进NoVaT型(LNG-CU-IUD,4号)和TCu-220 C(1号)各100例妇女使用18个月的避孕效果和可接受性。结果续用率以1号最高,达86.0％,4号最低,仅65.1％(P<0.05);妊娠率2号达2.0％,4号为0(P>0.05);脱落率3号达8.9％,4号仅1.0％(P<0.05);因症取出率4号达29.3％,明显高于其他3种(P<0.05)。3种LNG-IUD各有优缺点,在推广使用之前,尚需进一步调整药物释放量、改进IUD的形状和工艺。更多还原

【Abstract】 In this study 100 sujects bearing the key type IUD (K-LNG-IUD, No. 2), type IUD (C-LNG-IUD, No. 3), modified NOVA T (LNG-Cu-IUD, No. 4) and T-Cu C220 were observed by envelop method for 18 months for their con- traceptive effectiveness and acceptence rates. The No. 1 IUD had a highest continuation rate of 86.0 %, the No. 4 was the lowest of 65.1 % (P<0.05). No. 2 had the highest pregnancy rate of 2.0 % (No. 2) and No. 4 the lowest of 0. (P>0.05). No. 3 had the highest expulsion rate of 8.9 % (No. 3), while No. 4 the lowest of 1.0 % (P<0.05). No.1 had the highest discontinuation rate of 29.3 % caused by medical factors, which was markedly higher than that of the other three IUDs (P<0.05). LNG-IUDs can cause significant oligomenorrhea. Our experimental results indicate that each type of IUDs has its disadvantages as well as advantages. Consequently, futher sutdies must be carried out to adjust their releasing rate and improve their shape and technique before being widely employed.更多还原