【摘要】 对诺卡菌SP·61降解胆固醇边链至雄甾1.4-二烯3.17-二酮(ADD)的发酵条件研究,可以选择最佳的发酵条件,提高ADD的转化率。本文就部分培养基成分的改变、通气量、pH、乙醇以及底物诱导等因素进行研究,从而使ADD的克分子转化率提高到35％(底物浓度为1％,转化时间为84h)。更多还原

【Abstract】 This paper presents of studies on conditions for Nocardia sp. 61 fermentation cleavage of cholesterol to produce androsta-1, 4-diene-3, 17-dione (ADD).Optimal studies were undertaken for factors such as: Medium composition, alcohol concentration, pH, capacity of air input, effects of alcohol and substrate induce etc.The investigative efforts resulted in a 35% increase in ADD molar conversion yield under a 1‰ substrate concentration etc.更多还原